Proliferating Cell Nuclear Antigen Uses Two Distinct Modes to Move along DNA
نویسندگان
چکیده
منابع مشابه
Proliferating cell nuclear antigen uses two distinct modes to move along DNA.
Proliferating cell nuclear antigen (PCNA) plays an important role in eukaryotic genomic maintenance by topologically binding DNA and recruiting replication and repair proteins. The ring-shaped protein forms a closed circle around double-stranded DNA and is able to move along the DNA in a random walk. The molecular nature of this diffusion process is poorly understood. We use single-molecule ima...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2009
ISSN: 0021-9258
DOI: 10.1074/jbc.m109.008706